Nitric oxide and inflammatory joint diseases
نویسندگان
چکیده
منابع مشابه
Inducible nitric oxide synthase and inflammatory diseases.
Nitric oxide (NO) is a colorless gas at room temperature and one of the simplest molecules known, yet it has been implicated in a wide variety of regulatory mechanisms ranging from vasodilatation and blood pressure control to neurotransmission. It is also involved in nonspecific immunity and participates in the complex mechanism of tissue injury as a major mediator of inflammatory processes and...
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Interest in the role of free radicals in rheumatoid arthritis (RA) stems from the seminal work of McCord,' who noted the decreased viscosity of synovial fluid in RA patients and showed that a similar decrease could be produced by exposing synovial fluid, or solutions of hyaluronic acid, to a system generating superoxide radical, 02-. McCord's observations led to interest in the use of intraarti...
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In normal upper airways, nitric oxide is generated by the paranasal sinus epithelium and then diffuses into the nasal cavities. This study examined whether or not nasal NO concentration is affected by paranasal sinus inflammatory diseases. The influence of obstruction (nasal polyposis) and/or inflammation (allergy or chronic sinusitis) of the paranasal sinuses on nasal NO concentration was eval...
متن کاملNitric oxide and infectious diseases.
Nitric oxide (NO) has undergone something of an image change in recent years. Previously considered a pollutant from car exhausts, NO has now been implicated in many physiological processes. Here we review the dual roles of NO in infection—as a critical agent of host defence but also as a central mediator of pathogenesis—using septic shock, bacterial meningitis, and malaria to illustrate some c...
متن کاملInflammatory Joint Diseases
1Department of Rheumatology and Clinical Immunology, The First Hospital of Xiamen University, Xiamen 361003, China 2Buffalo General Medical Center, State University of New York at Buffalo School of Medicine, Buffalo, NY 14203, USA 3Department of Rheumatology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200001, China 4Division of Allergy, Immunology and Rheumatolog...
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ژورنال
عنوان ژورنال: Rheumatology
سال: 1998
ISSN: 1462-0324,1462-0332
DOI: 10.1093/rheumatology/37.3.246